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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YWHAB All Species: 35.76
Human Site: T143 Identified Species: 60.51
UniProt: P31946 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31946 NP_003395.1 246 28082 T143 S G D N K Q T T V S N S Q Q A
Chimpanzee Pan troglodytes XP_528202 382 42115 I278 A G D D K K G I V D Q S Q Q A
Rhesus Macaque Macaca mulatta XP_001109676 245 27935 T142 S G D N K Q T T V S N S Q Q A
Dog Lupus familis XP_852754 244 27832 T141 S G D N K Q T T V S N S Q Q A
Cat Felis silvestris
Mouse Mus musculus Q9CQV8 246 28068 T143 S G E N K Q T T V S N S Q Q A
Rat Rattus norvegicus P35213 246 28036 T143 S G D N K Q T T V S N S Q Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518806 277 31320 T174 S G D N K Q T T V S N S Q Q A
Chicken Gallus gallus Q5ZLQ6 244 27889 T141 S G D N K Q T T V A N S Q Q A
Frog Xenopus laevis Q5XHK2 244 27740 T141 S G D S K Q E T V A S S Q Q A
Zebra Danio Brachydanio rerio Q5PRD0 244 27628 T141 S G D S K R T T V E N S Q K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29310 248 28209 V144 T G D A R N T V V D D S Q T A
Honey Bee Apis mellifera XP_391841 247 28058 V143 T G E T R N A V V D D S Q K A
Nematode Worm Caenorhab. elegans Q20655 248 28049 V143 S G D D R N S V V E K S Q Q S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P34730 273 31043 A146 S G D A R E K A T N S S L E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 99.5 99.1 N.A. 98.7 98.3 N.A. 88.4 97.1 87.4 90.6 N.A. 78.6 80.5 78.2 N.A.
Protein Similarity: 100 60.7 99.5 99.1 N.A. 99.1 98.7 N.A. 88.4 98.7 94.3 96.3 N.A. 89.5 90.2 87.5 N.A.
P-Site Identity: 100 53.3 100 100 N.A. 93.3 100 N.A. 100 93.3 73.3 73.3 N.A. 46.6 33.3 46.6 N.A.
P-Site Similarity: 100 73.3 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 66.6 66.6 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 59.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 71.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 0 8 8 0 15 0 0 0 0 93 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 86 15 0 0 0 0 0 22 15 0 0 0 0 % D
% Glu: 0 0 15 0 0 8 8 0 0 15 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 100 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 72 8 8 0 0 0 8 0 0 15 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 50 0 22 0 0 0 8 58 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 58 0 0 0 0 8 0 93 72 0 % Q
% Arg: 0 0 0 0 29 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 79 0 0 15 0 0 8 0 0 43 15 100 0 0 8 % S
% Thr: 15 0 0 8 0 0 65 65 8 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 22 93 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _